Science week

Next 21st November at 9:30h, students from the Scientific and Technological Branch will explain “How do drugs work” using Pecha Kucha presentations at Auditori of Centre Cultural (Martorell). A Pecha Kucha is a type of presentation style in which 20 slides are shown for 20 seconds each (six minutes and 40 seconds in total). The format, which keeps presentations concise and fast-paced, powers students to present results in a professional format using only evidence based medicine.Every two students will present scientific information of a well known prescription drug, that is, drug name, drug receptor using protein data bank database, mechanism of action of the drug with the receptor based on original scientific articles, drug main and adverse effects, and, references. More information at www.formaciovirtual.com/cs.
After that, at 12 h, students from the Technological Branch will explain “How to program software and objects” using Pecha Kucha. There will be examples of creating simple mobile apps using Processing.org 2.0.3 software and Android SDK. Basic examples using Arduino/Processing software to control simple sensors as light dependent resistor (LDR), actuators like light emitting diodes (LEDs) that could act as an analog input, analog output, digital input and digital output. It will be shown also examples of Processing code to create interactive activities including audio, video, text, augmented reality examples, computer vision examples, and genetic algorithms and neural networks, among others. The students will explain how the code make possible to work the corresponding application.

Enclosed you will find our students giving presentations during the Science Week taking place every year in November at Centre Cultural de Martorell.

The protein song:

Amoxicillin

Fluoxetine

Insulin

Nortriptyline

PARACETAMOL

Salbutamol

TAXOL

MOLECULAR DOCKING FOR INFECTIONS

Research in pathophysiology and pharmacology

dockingexample
docking

1. African sleeping sickness (African trypanosomiasis) Trypanosoma brucei (eflornitine, nifurtimox, melarsoprol, pentamidine, suramine—cyclic AMC phosphodiesterase, TbM32 protease and ACE2 as model)
2. Amebiasis Entamoeba histolytica (auranofin adn thioredoxin reductase, paromycin, chloroquine)
3. Anthrax Bacillus anthracis (3 proteins in toxin: lethal factor, edema factor and protective antigen against raxibacumab, and ciprofloxacin and others against polyD-glutamic acid capsule)
4. Bacterial vaginosis (BV) multiple bacteria (Gardnerella vaginalis, metronidazol and tetraciclin against ferredoxin oxidorectuctase and CYP2C9 )
5- Botulism botulinum toxin (BoNT-A and E against SNAP25, BoNT B, D and F against synaptobrevin and C aganst syntaxin)
6. Bubonic plague the bacterial family Enterobacteriaceae (Yersinia pestis, streptomycin receptor in the ribosome)
7. Syphilis Treponema pallidum (penicillin and penicillin binding proteins)
8. Tetanus Clostridium tetani (neurotoxin receptor and gangliosides His1293, His1270, Trp 1288,… check!)
9. Gonorrhea Neisseria gonorrhoeae (azithromycin, ceftriaxone, doxycycline against cellular adherssion CEACAM1, CEACAM3, CR3, CD46)
10. SARS (Severe Acute Respiratory Syndrome) SARS coronavirus (ribavirin,oseltamivir, foscarnet against S-protein-ACE2, SARS-CoV M, papain-like protease 2, SARS.CoV RdRp, SARS-CoV helicase)
11. Influenza (flu) Orthomyxoviridae family (oseltamivir and neuroaminidase)
12. Salmonellosis Salmonella genus (antibiotic resistant with cefotaxime, cephalothin, imipenem against D-Ala-D-Ala peptidase and penicillin binding protein 3)
13. Candidiasis (Moniliasis; Thrush) usually Candida albicans and other Candida species (clotrimazole, ketoconazole, fluconazole, itraconazole, amphotericine B, nystatine agins Erg11p lanosterol14 alpha demethylase and CDR1, CDR2 for drug resistance)
14. Cholera Vibrio cholerae (toxin, erythromycin and tetracyclin for protein disulfide isomerase, Arf6, guanyl nucleotide binding protein of the adenylate cyclase system)
15. Clostridium difficile infection Clostridium difficile (metronidazole; vancomycin for histidine kinase VanSsc)
16. Common cold (Acute viral rhinopharyngitis; Acute coryza) usually rhinoviruses and coronaviruses (pleconaril for human rhinovirus VP1 Thyr152,Val191, VP2, VP4, etc)
17. Creutzfeldt-Jakob disease (CJD) PRNP (imiquimod for TLR7, prion for amyloid receptor beta, 37kD laminin receptor in extracellular matrix)
18. Dengue fever Dengue viruses (DEN-1, DEN-2, DEN-3 and DEN-4) (5-Aza-7-deazaguanosine for protease inhibitor or Non Structural protein NS3 and NS5 and project Discovering Dengue Drugs Together)
19. Diphtheria Corynebacterium diphtheriae (toxin against heparin binding epidermal growth factor similar to NAD+diphtamide ADP-ribosyltransferase)
Alumnes de Batxillerat científic i tecnològic que presentaran els seus resultats de docking al Centre Cultural de Martorell el dimarts 18 de novembre de 2014 dintre de la Setmana de la Ciència a Catalunya 2014: Albert Andrés, Sergi Bosquet, Laura Buch, Luis Casanova, Pol Cesáreo, Alba Cifuentes, Cristian Danoz, Hadia Drame, Souhaila El Bahkti, Ali El Kouazi, Omar Espinoza, Silvai Fuertes, Alan Gallego, Oriol Gil, M. Angel Gracia, Elisabeth Hernan, Imad Laamri, Agustín López, Oscar Lorente, Ariadna Lozano, Esther Martín, Joan Mataró, Adrián Mora, Paula Munné, Manuel Muñoz, Elsa Naranjo, Cèlia Ortega, Adriana Pla, Ferran Povill, Guillem Ripoll, Laura Romero, Angel Rozalen, Cora Rufian, Julia Sosa, Carla Viñals, Lourdes Yébenes Professor de “Contemporary Sciences”: Francesc Pérez

USBs
Students of Contemporary Sciences presented results on medicinal plant monographs and scientific postersat Centre Cultural de Martorell.


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